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The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling

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dc.contributor.author Banks, Susan M. L.
dc.contributor.author Cho, Bomsoo
dc.contributor.author Eun, Eun
dc.contributor.author Lee, Ji-Hoon
dc.contributor.author Windler, Sarah L
dc.contributor.author Xie, Xuanhua
dc.contributor.author Bilder, David
dc.contributor.author Fischer, Janice A.
dc.date.accessioned 2018-03-28T00:33:49Z
dc.date.available 2018-03-28T00:33:49Z
dc.date.issued 2011-03-23
dc.identifier.citation Banks, S. L., Cho, B., Eun, S. H., Lee, J., Windler, S. L., Xie, X., & ... Fischer, J. A. (2011). The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling. Plos One, 6(3), e18259. doi:10.1371/journal.pone.0018259 en_US
dc.identifier.issn 1932-6203 (Electronic)
dc.identifier.uri http://hdl.handle.net/11416/378
dc.identifier.uri https://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=mdc&AN=21448287&scope=site&custid=s5615486
dc.description.abstract Notch signaling requires ligand internalization by the signal sending cells. Two endocytic proteins, epsin and auxilin, are essential for ligand internalization and signaling. Epsin promotes clathrin-coated vesicle formation, and auxilin uncoats clathrin from newly internalized vesicles. Two hypotheses have been advanced to explain the requirement for ligand endocytosis. [...] en_US
dc.language.iso en_US en_US
dc.publisher Public Library of Science en_US
dc.subject Endocytosis en_US
dc.subject Signal Transduction en_US
dc.subject Drosophila Proteins en_US
dc.subject Receptors, Notch en_US
dc.subject rab GTP-Binding Proteins en_US
dc.subject Vesicular Transport Proteins en_US
dc.title The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling en_US
dc.type Article en_US


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