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Auxilin is essential for Delta signaling

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dc.contributor.author Eun, Suk Ho
dc.contributor.author Banks, Susan M. L.
dc.contributor.author Fischer, Janice A.
dc.date.accessioned 2018-03-28T00:40:45Z
dc.date.available 2018-03-28T00:40:45Z
dc.date.issued 2008-03
dc.identifier.citation Eun, S. H., Banks, S. L., & Fischer, J. A. (2008). Auxilin is essential for Delta signaling. Development (Cambridge, England), 135(6), 1089-1095. doi:10.1242/dev.009530 en_US
dc.identifier.issn 0950-1991 (Print)
dc.identifier.uri http://hdl.handle.net/11416/379
dc.identifier.uri https://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=mdc&AN=18256200&scope=site&custid=s5615486
dc.description.abstract Endocytosis regulates Notch signaling in both signaling and receiving cells. A puzzling observation is that endocytosis of transmembrane ligand by the signaling cells is required for Notch activation in adjacent receiving cells. A key to understanding why signaling depends on ligand endocytosis lies in identifying and understanding the functions of crucial endocytic proteins. One such protein is Epsin, an endocytic factor first identified in vertebrate cells. Here, we show in Drosophila that Auxilin, an endocytic factor that regulates Clathrin dynamics, is also essential for [...] en_US
dc.language.iso en_US en_US
dc.publisher Company Of Biologists Limited en_US
dc.subject Auxilins en_US
dc.subject Drosophila Proteins en_US
dc.subject Membrane Proteins en_US
dc.subject Adaptor Proteins en_US
dc.subject Intracellular Signaling Peptides and Proteins en_US
dc.title Auxilin is essential for Delta signaling en_US
dc.type Article en_US


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