Reducing synuclein accumulation improves neuronal survival after spinal cord injury
| dc.contributor.author | Fogerson, Stephanie M. | |
| dc.contributor.author | van Brummen, Alexandra J. | |
| dc.contributor.author | Busch, David J. | |
| dc.contributor.author | Allen, Scott R. | |
| dc.contributor.author | Roychaudhuri, Robin | |
| dc.contributor.author | Banks, Susan M. L. | |
| dc.contributor.author | Klärner, Frank-Gerrit | |
| dc.contributor.author | Schrader, Thomas | |
| dc.contributor.author | Bitan, Gal | |
| dc.contributor.author | Morgan, Jennifer R. | |
| dc.date.accessioned | 2018-03-28T00:07:52Z | |
| dc.date.available | 2018-03-28T00:07:52Z | |
| dc.date.issued | 2016-04 | |
| dc.description.abstract | Spinal cord injury causes neuronal death, limiting subsequent regeneration and recovery. Thus, there is a need to develop strategies for improving neuronal survival after injury. Relative to our understanding of axon regeneration, comparatively little is known about the mechanisms that promote the survival of damaged neurons. To address this, we took advantage of lamprey giant reticulospinal neurons whose large size permits detailed examination of post-injury molecular responses at the level of individual, identified cells.[...] | en_US |
| dc.identifier.citation | Fogerson, S. M., van Brummen, A. J., Busch, D. J., Allen, S. R., Roychaudhuri, R., Banks, S. M., & ... Morgan, J. R. (2016). Reducing synuclein accumulation improves neuronal survival after spinal cord injury. Experimental Neurology, 278105-115. doi:10.1016/j.expneurol.2016.02.004 | en_US |
| dc.identifier.issn | 0014-4886 | |
| dc.identifier.uri | http://hdl.handle.net/11416/376 | |
| dc.identifier.uri | https://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=edselp&AN=S0014488616300267&site=eds-live&scope=site&custid=s5615486 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Elsevier Inc. | en_US |
| dc.subject | CLR01 | en_US |
| dc.subject | Lamprey | en_US |
| dc.subject | Molecular tweezer | en_US |
| dc.subject | Neurodegeneration | en_US |
| dc.subject | Parkinson's disease | en_US |
| dc.subject | Synaptotagmin | en_US |
| dc.title | Reducing synuclein accumulation improves neuronal survival after spinal cord injury | en_US |
| dc.type | Article | en_US |