Reducing synuclein accumulation improves neuronal survival after spinal cord injury

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dc.contributor.authorFogerson, Stephanie M.
dc.contributor.authorvan Brummen, Alexandra J.
dc.contributor.authorBusch, David J.
dc.contributor.authorAllen, Scott R.
dc.contributor.authorRoychaudhuri, Robin
dc.contributor.authorBanks, Susan M. L.
dc.contributor.authorKlärner, Frank-Gerrit
dc.contributor.authorSchrader, Thomas
dc.contributor.authorBitan, Gal
dc.contributor.authorMorgan, Jennifer R.
dc.date.accessioned2018-03-28T00:07:52Z
dc.date.available2018-03-28T00:07:52Z
dc.date.issued2016-04
dc.description.abstractSpinal cord injury causes neuronal death, limiting subsequent regeneration and recovery. Thus, there is a need to develop strategies for improving neuronal survival after injury. Relative to our understanding of axon regeneration, comparatively little is known about the mechanisms that promote the survival of damaged neurons. To address this, we took advantage of lamprey giant reticulospinal neurons whose large size permits detailed examination of post-injury molecular responses at the level of individual, identified cells.[...]en_US
dc.identifier.citationFogerson, S. M., van Brummen, A. J., Busch, D. J., Allen, S. R., Roychaudhuri, R., Banks, S. M., & ... Morgan, J. R. (2016). Reducing synuclein accumulation improves neuronal survival after spinal cord injury. Experimental Neurology, 278105-115. doi:10.1016/j.expneurol.2016.02.004en_US
dc.identifier.issn0014-4886
dc.identifier.urihttp://hdl.handle.net/11416/376
dc.identifier.urihttps://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=edselp&AN=S0014488616300267&site=eds-live&scope=site&custid=s5615486
dc.language.isoen_USen_US
dc.publisherElsevier Inc.en_US
dc.subjectCLR01en_US
dc.subjectLampreyen_US
dc.subjectMolecular tweezeren_US
dc.subjectNeurodegenerationen_US
dc.subjectParkinson's diseaseen_US
dc.subjectSynaptotagminen_US
dc.titleReducing synuclein accumulation improves neuronal survival after spinal cord injuryen_US
dc.typeArticleen_US
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