The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling

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dc.contributor.authorBanks, Susan M. L.
dc.contributor.authorCho, Bomsoo
dc.contributor.authorEun, Eun
dc.contributor.authorLee, Ji-Hoon
dc.contributor.authorWindler, Sarah L
dc.contributor.authorXie, Xuanhua
dc.contributor.authorBilder, David
dc.contributor.authorFischer, Janice A.
dc.date.accessioned2018-03-28T00:33:49Z
dc.date.available2018-03-28T00:33:49Z
dc.date.issued2011-03-23
dc.description.abstractNotch signaling requires ligand internalization by the signal sending cells. Two endocytic proteins, epsin and auxilin, are essential for ligand internalization and signaling. Epsin promotes clathrin-coated vesicle formation, and auxilin uncoats clathrin from newly internalized vesicles. Two hypotheses have been advanced to explain the requirement for ligand endocytosis. [...]en_US
dc.identifier.citationBanks, S. L., Cho, B., Eun, S. H., Lee, J., Windler, S. L., Xie, X., & ... Fischer, J. A. (2011). The functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recycling. Plos One, 6(3), e18259. doi:10.1371/journal.pone.0018259en_US
dc.identifier.issn1932-6203 (Electronic)
dc.identifier.urihttp://hdl.handle.net/11416/378
dc.identifier.urihttps://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=mdc&AN=21448287&scope=site&custid=s5615486
dc.language.isoen_USen_US
dc.publisherPublic Library of Scienceen_US
dc.subjectEndocytosisen_US
dc.subjectSignal Transductionen_US
dc.subjectDrosophila Proteinsen_US
dc.subjectReceptors, Notchen_US
dc.subjectrab GTP-Binding Proteinsen_US
dc.subjectVesicular Transport Proteinsen_US
dc.titleThe functions of auxilin and Rab11 in Drosophila suggest that the fundamental role of ligand endocytosis in notch signaling cells is not recyclingen_US
dc.typeArticleen_US

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