Auxilin is essential for Delta signaling

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dc.contributor.authorEun, Suk Ho
dc.contributor.authorBanks, Susan M. L.
dc.contributor.authorFischer, Janice A.
dc.date.accessioned2018-03-28T00:40:45Z
dc.date.available2018-03-28T00:40:45Z
dc.date.issued2008-03
dc.description.abstractEndocytosis regulates Notch signaling in both signaling and receiving cells. A puzzling observation is that endocytosis of transmembrane ligand by the signaling cells is required for Notch activation in adjacent receiving cells. A key to understanding why signaling depends on ligand endocytosis lies in identifying and understanding the functions of crucial endocytic proteins. One such protein is Epsin, an endocytic factor first identified in vertebrate cells. Here, we show in Drosophila that Auxilin, an endocytic factor that regulates Clathrin dynamics, is also essential for [...]en_US
dc.identifier.citationEun, S. H., Banks, S. L., & Fischer, J. A. (2008). Auxilin is essential for Delta signaling. Development (Cambridge, England), 135(6), 1089-1095. doi:10.1242/dev.009530en_US
dc.identifier.issn0950-1991 (Print)
dc.identifier.urihttp://hdl.handle.net/11416/379
dc.identifier.urihttps://search.ebscohost.com/login.aspx?direct=true&AuthType=shib&db=mdc&AN=18256200&scope=site&custid=s5615486
dc.language.isoen_USen_US
dc.publisherCompany Of Biologists Limiteden_US
dc.subjectAuxilinsen_US
dc.subjectDrosophila Proteinsen_US
dc.subjectMembrane Proteinsen_US
dc.subjectAdaptor Proteinsen_US
dc.subjectIntracellular Signaling Peptides and Proteinsen_US
dc.titleAuxilin is essential for Delta signalingen_US
dc.typeArticleen_US

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